Sodium Citrate (anhydrous, dihydrate)
- Benchmark: Benchmark 3
- Assessed: 2025-11-14
- Expires: 2029-03-18
Used primarily in Cosmetics & Personal Care, Industrial / Manufacturing, Pharmaceuticals, and Solvents & Cleaning applications, Sodium Citrate (anhydrous, dihydrate) is specifically used in buffer, chelating agent, colorant, emulsifier, flavoring agent, food additive, nutrient supplement, ph control agent, processing aid, stabilizer, and surfactant.
Sodium citrate functions as a buffering agent, emulsifier/emulsifier salt, color or coloring adjunct,
flavoring agent or adjuvant, malting or fermenting aid, nutrient supplement, pH control agent,
sequestrant/chelant, stabilizer, thickener, or surface-active agent (EC 2024, U.S. FDA 2024). It is
produced via addition of sodium carbonate or sodium sulfate to citric acid (HSDB 2002). The United
States Food and Drug Administration (U.S. FDA) recognizes sodium citrate as an indirect food additive
under 21 CFR §175.300, as a prior-sanctioned ingredient under 21 CFR §181.29, and as generally
recognized as safe (GRAS) under 21 CFR §184.1751 (U.S. FDA 2024). The Cosmetic Ingredient
Review (CIR) Expert Panel concluded sodium citrate is safe for use in cosmetics in the present practices
of use and concentration (up to 10% in rinse-off and leave-on products) (CIR 2014).
Chemical Synonyms CAS #68-04-2: Trisodium citrate; 2-Hydroxy-1,2,3-propanetricarboxylic acid, trisodium salt, anhydrous; 2-Hydroxy-1,2,3-propanetricarboxylic acid, trisodium salt; 2-Hydroxy-1,2,3- propanetricarboxylic acid trisodium salt; 1,2,3-propanetricarboxylic acid, 2-hydroxy -, trisodium salt; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt (1:3); Trisodium 2-hydroxypropane-1,2,3- tricarboxylate; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt; Citric acid, trisodium salt; CITRATE, TRISODIUM; Cystemme; Citrosodine; Citrosodina; Citreme; citrato de trisodio; Citrate de trisodium; Citnatin; Urisal; Unifine P 3; Ional; Citra-lock (U.S. EPA 2024a). EC 200-675-3 (ECHA 2024). CAS #994-36-5: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt (1:?); citric acid, sodium salt; Sodium citrate (x:1); 1,2,3- Propanetricarboxylic acid, 2-hydroxy-, sodium salt (1:x); Citric acid sodium salt; 2-Hydroxy-1,2,3- propanetricarboxylic acid sodium salt (1:?); Sodium 2-hydroxy-1,2,3-propanetricarboxylate; Cellmic ; MB 9082; E 331; Acide citrique, sel de sodium; acido citrico, sal de sodio; Bicitra; Pneucid; Zitronensaure, Natriumsalz; EINECS 213-618-2 (U.S. EPA 2024a). EC 213-618-2 (ECHA 2024). CAS #6132-04-3: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt, hydrate (1:3:2); Sodium 2-hydroxypropane- 1,2,3-tricarboxylate--water (3/1/2); Trisodium citrate dihydrate; 1,2,3-Propanetricarboxylic acid, 2- hydroxy-, trisodium salt, dihydrate; 2-Hydroxy-1,2,3-propanetricarboxylic acid, trisodium salt, dihydrate; citrate, sodium, dihydrate; citrate, trisodium, 2-hydrate; citric acid, trisodium salt, dihydrate; natriumcitrat-dihydrat; sodium citrate dihydrate; trisodium-2-hydroxypropane-1,2,3-tricarboxylate dihydrate; 2-hydroxy-1,2,3-propanetricarboxylic acid trisodium salt dihydrate; Citronensaeure,Trinatrium-Salz-Dihydrat; Natrum citricum; Sodium citrate hydrate; UNII-B22547B95K (U.S. EPA 2024a). EC 612-118-5 (ECHA 2024).
Key Functions: Cosmetics & Personal Care, Industrial / Manufacturing, Pharmaceuticals, Solvents & Cleaning